Interleukin-1β mediates LPS-induced inhibition of apoptosis in retinoic acid-differentiated HL-60 cells

Promyelocytic HL-60 cells differentiated to a neutrophilic phenotype by incubation with all-trans retinoic acid become constitutively apoptotic. Exposure to either LPS or IL-1β inhibited the apoptosis of differentiated HL-60 cells. LPS induced the expression of pro-IL-1β message, upregulated the act...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Biochemical and biophysical research communications 2008-05, Vol.369 (2), p.532-538
Hauptverfasser:	Marshall, John C., Jia, Song Hui, Parodo, Jean, Watson, R. William G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Caspase-1 HL-60 cells Inflammation Innate immunity Interleukin-1 Neutrophil
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!