Locoregional Radiation Therapy in Patients With High-Risk Breast Cancer Receiving Adjuvant Chemotherapy: 20-Year Results of the British Columbia Randomized Trial

Background: The British Columbia randomized radiation trial was designed to determine the survival impact of locoregional radiation therapy in premenopausal patients with lymph node–positive breast cancer treated by modified radical mastectomy and adjuvant chemotherapy. Three hundred eighteen patien...

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Veröffentlicht in:	JNCI : Journal of the National Cancer Institute 2005-01, Vol.97 (2), p.116-126
Hauptverfasser:	Ragaz, Joseph, Olivotto, Ivo A., Spinelli, John J., Phillips, Norman, Jackson, Stewart M., Wilson, Kenneth. S., Knowling, Margaret A., Coppin, Christopher M. L., Weir, Lorna, Gelmon, Karen, Le, Nhu, Durand, Ralph, Coldman, Andrew J., Manji, Mohamed
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Breast cancer Breast Neoplasms - drug therapy Breast Neoplasms - mortality Breast Neoplasms - pathology Breast Neoplasms - radiotherapy Breast Neoplasms - surgery British Columbia Chemotherapy Chemotherapy, Adjuvant Cyclophosphamide - administration & dosage Disease-Free Survival Female Fluorouracil - administration & dosage Follow-Up Studies Genital system. Mammary gland Humans Lymph Nodes - pathology Lymph Nodes - radiation effects Lymphatic Metastasis Mastectomy, Modified Radical Medical research Medical sciences Methotrexate - administration & dosage Neoplasm Recurrence, Local - mortality Neoplasm Recurrence, Local - prevention & control Proportional Hazards Models Radiation Radiotherapy, Adjuvant - adverse effects Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Risk Assessment Survival Analysis Therapy Treatment Outcome Tumors
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