Effect of fermented seed extract of Carica papaya on litters of female wistar rats (Rattus norvegicus)

Effect of fermented seed extract of Carica papaya on litters of female wistar rats (Rattus norvegicus)

This study was performed to determine the effects of fermented seeds of Carica papaya on litters of female Wistar rats, and ascertain its safety as a food condiment. Animals in group one served as control, and were given only water; those in groups two and three were given the aqueous extract of the...

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Veröffentlicht in:African journal of biotechnology 2009-03, Vol.8 (5), p.854-857
Hauptverfasser: Abdulazeez, MA, Ameh, AD, Ibrahim, S, Ayo, JO, Ambali, S F
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Carica papaya
Rattus norvegicus
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creator Abdulazeez, MA
Ameh, AD
Ibrahim, S
Ayo, JO
Ambali, S F
description This study was performed to determine the effects of fermented seeds of Carica papaya on litters of female Wistar rats, and ascertain its safety as a food condiment. Animals in group one served as control, and were given only water; those in groups two and three were given the aqueous extract of the fermented seeds of C. papaya at 500 and 1500 mg/kg, respectively, from gestation day six to gestation day 15, kept till terms and allowed to litter. Results showed that the percentage increase in weight of rats in the control group was not significant (P
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Animals in group one served as control, and were given only water; those in groups two and three were given the aqueous extract of the fermented seeds of C. papaya at 500 and 1500 mg/kg, respectively, from gestation day six to gestation day 15, kept till terms and allowed to litter. Results showed that the percentage increase in weight of rats in the control group was not significant (P&lt;0.05) when compared to those administered the fermented extract at 500 and 1500 mg/kg. There was no significant difference (P&lt;0.05) in litter size and litter body weight in rats within all the groups, compared to the control group. Also, the anogenital distance (AGD) to crown rump length (CRL) ratio in rats dosed with the fermented extract of C. papaya seeds at 500 and 1500 mg/kg was not significantly different from the control group. 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subjects Carica papaya
Rattus norvegicus
title Effect of fermented seed extract of Carica papaya on litters of female wistar rats (Rattus norvegicus)
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