CYP51—the omnipotent P450

Sterol 14α-demethylase (CYP51) is the single cytochrome P450 (CYP) required for sterol biosynthesis in different phyla, and it is the most widely distributed P450 gene family being found in all biological kingdoms. It catalyzes the first step following cyclization in sterol biosynthesis such as remo...

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Veröffentlicht in:	Molecular and cellular endocrinology 2004-02, Vol.215 (1), p.165-170
Hauptverfasser:	Lepesheva, Galina I, Waterman, Michael R
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acid sequence alignment Animals Cytochrome P-450 Enzyme System - chemistry Cytochrome P-450 Enzyme System - physiology Cytochrome P450 Evolution, Molecular Humans Mutagenesis, Site-Directed Mycobacterium tuberculosis Mycobacterium tuberculosis - enzymology Mycobacterium tuberculosis - genetics Oxidation-Reduction Oxidoreductases - chemistry Oxidoreductases - genetics Oxidoreductases - physiology Site-directed mutagenesis Sterol 14-Demethylase Sterol 14α-demethylase Sterol biosynthesis
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