Effects of insulin-like growth factor-1 on endoplasmic reticulum stress and autophagy in rat gastric smooth muscle cells cultured at different glucose concentrations in vitro

The purpose of the study was to observe changes in endoplasmic reticulum stress (ERS)- and autophagy-related proteins in gastric smooth muscle tissues of diabetic rats with gastroparesis, investigate the effect of insulin-like growth factor 1 (IGF-1) on ERS and autophagy in rat gastric smooth muscle...

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Veröffentlicht in:	Molecular and cellular biochemistry 2019-01, Vol.451 (1-2), p.11-20
Hauptverfasser:	Fang, Xue-sen, Zhang, Mo-han, Guo, Jun-yu, Jin, Zheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autophagy Biochemistry Biomedical and Life Sciences Cardiology Cell culture Cells, Cultured CHOP protein Deoxyribonucleic acid Diabetes Diabetes mellitus Diabetes Mellitus, Experimental - drug therapy Diabetes Mellitus, Experimental - metabolism Diabetes Mellitus, Experimental - pathology DNA DNA damage Endoplasmic reticulum Endoplasmic Reticulum Stress Glucose Glucose - pharmacology Immunofluorescence In Vitro Techniques Insulin Insulin-like growth factor I Insulin-Like Growth Factor I - pharmacology Insulin-like growth factors Life Sciences Male Medical Biochemistry Microscopy Microtubule-associated protein 1 Muscles Myocytes, Smooth Muscle - drug effects Myocytes, Smooth Muscle - metabolism Myocytes, Smooth Muscle - pathology Oncology Phagocytosis Proteins Rats Rats, Sprague-Dawley Rodents Scanning microscopy Signal Transduction Smooth muscle Stomach - drug effects Stomach - pathology
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