Immune thrombocytopenia: Effectiveness of frontline steroids and comparison of azathioprine, splenectomy, and rituximab as second‐line treatment

Objective For immune thrombocytopenia (ITP), efficacy of frontline steroids is well established. However, clinical data comparing various treatment options for refractory or relapsed ITP are limited. We aimed to investigate the outcome of frontline steroid treatment for ITP patients and compare comm...

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Veröffentlicht in:	European journal of haematology 2018-10, Vol.101 (4), p.549-555
Hauptverfasser:	Chang, Hung, Tang, Tzung‐Chih, Hung, Yu‐Shin, Li, Pei‐Ling, Kuo, Ming‐Chung, Wu, Jin‐Hou, Wang, Po‐Nan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Azathioprine Azathioprine - administration & dosage Azathioprine - adverse effects Azathioprine - therapeutic use Biomarkers Combined Modality Therapy Diagnosis Female Humans Idiopathic thrombocytopenic purpura immune thrombocytopenia Immunosuppressive Agents - administration & dosage Immunosuppressive Agents - adverse effects Immunosuppressive Agents - therapeutic use Immunotherapy Male Medical records Middle Aged Monoclonal antibodies Patients Purpura, Thrombocytopenic, Idiopathic - diagnosis Purpura, Thrombocytopenic, Idiopathic - mortality Purpura, Thrombocytopenic, Idiopathic - therapy Retreatment Retrospective Studies Rituximab Rituximab - administration & dosage Rituximab - adverse effects Rituximab - therapeutic use Splenectomy Splenectomy - methods Steroid hormones Steroids Steroids - administration & dosage Steroids - adverse effects Steroids - therapeutic use Survival Analysis Thrombocytopenia Treatment Outcome Young Adult
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