Efficacy and safety of bilastine 20 mg compared with cetirizine 10 mg and placebo for the symptomatic treatment of seasonal allergic rhinitis: a randomized, double-blind, parallel-group study

Summary Background Bilastine is a new non‐sedative H1 receptor antagonist, indicated for the treatment of allergic rhinitis (AR) (seasonal and perennial). Objective To assess and compare the efficacy and safety of bilastine 20 mg vs. cetirizine 10 mg and placebo in relieving the symptoms of seasonal...

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Veröffentlicht in:	Clinical and experimental allergy 2009-09, Vol.39 (9), p.1338-1347
Hauptverfasser:	Kuna, P., Bachert, C., Nowacki, Z., Van Cauwenberge, P., Agache, I., Fouquert, L., Roger, A., Sologuren, A., Valiente, R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Benzimidazoles - administration & dosage Benzimidazoles - adverse effects bilastine Biological and medical sciences cetirizine Cetirizine - administration & dosage Cetirizine - adverse effects Child Double-Blind Method Female Fundamental and applied biological sciences. Psychology Fundamental immunology H1 antihistamine Histamine H1 Antagonists, Non-Sedating - administration & dosage Histamine H1 Antagonists, Non-Sedating - adverse effects Humans Male Medical sciences Middle Aged nasal symptoms score Non tumoral diseases non-nasal symptoms score Otorhinolaryngology. Stomatology Piperidines - administration & dosage Piperidines - adverse effects Receptors, Histamine H1 - metabolism Rhinitis, Allergic, Seasonal - drug therapy Rhinitis, Allergic, Seasonal - metabolism seasonal allergic rhinitis Time Factors total symptom score Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology
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