SPTLC1 Binds ABCA1 To Negatively Regulate Trafficking and Cholesterol Efflux Activity of the Transporter super([dagger])

ABCA1 transport of cholesterol and phospholipids to nascent HDL particles plays a central role in lipoprotein metabolism and macrophage cholesterol homeostasis. ABCA1 activity is regulated both at the transcriptional level and at the post-translational level. To explore mechanisms involved in the po...

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Veröffentlicht in:	Biochemistry (Easton) 2008-01, Vol.47 (23), p.6138-6147
Hauptverfasser:	Benita, Yair, Latz, Eicke, Xavier, Ramnik J, Zhou, Suiping, Hornemann, Thorsten, Fitzgerald, Michael L, Zhuang, Debbie Z, Okuhira, Keiichiro, von Eckardstein, Arnold, Tamehiro, Norimasa, Brown, Cari E, Freeman, Mason W
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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