The Splicing Factor RNA-Binding Fox Protein 1 Mediates the Cellular Immune Response in Drosophila melanogaster

The uptake and destruction of bacteria by phagocytic cells is an essential defense mechanism in metazoans. To identify novel genes involved in the phagocytosis of , a major human pathogen, we assessed the phagocytic capacity of adult blood cells (hemocytes) of the fruit fly, by testing several lines...

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Veröffentlicht in:	The Journal of immunology (1950) 2018-08, Vol.201 (4), p.1154-1164
Hauptverfasser:	Nazario-Toole, Ashley E, Robalino, Javier, Okrah, Kwame, Corrada-Bravo, Hector, Mount, Stephen M, Wu, Louisa P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood cells Cell Adhesion Molecules - genetics Cell Adhesion Molecules - metabolism Down's syndrome Drosophila Drosophila melanogaster Drosophila melanogaster - immunology Drosophila Proteins - genetics Drosophila Proteins - metabolism FOX protein Fruit flies Gene Knockout Techniques Genetic diversity Hemocytes Hemocytes - immunology Humans Immune response Immune response (cell-mediated) Immunity, Cellular Immunoglobulins Insects Phagocytes Phagocytosis Ribonucleic acid RNA RNA Splicing Factors - genetics RNA Splicing Factors - metabolism RNA-Binding Proteins - genetics RNA-Binding Proteins - metabolism Splicing factors Staphylococcal Infections - genetics Staphylococcal Infections - immunology Staphylococcus aureus - physiology
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