Expression of intercellular adhesion molecule (ICAM)-1 or ICAM-2 is critical in determining sensitivity of pancreatic cancer cells to cytolysis by human gamma delta -T cells: Implications in the design of gamma delta -T-cell-based immunotherapies for pancreatic cancer

AbstractBackground and Aims: gamma delta -T cells can recognize and kill malignant cells, particularly those of epithelial origin, through mechanisms which do not require the recognition of tumor-specific antigens (innate immune response). This natural ability of gamma delta -T cells to kill tumor c...

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Veröffentlicht in:Journal of gastroenterology and hepatology 2009-05, Vol.24 (5), p.900-911
Hauptverfasser: Liu, Zhiyong, Guo, Ben, Lopez, Richard D
Format: Artikel
Sprache:eng
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