Cold-induced epigenetic programming of the sperm enhances brown adipose tissue activity in the offspring

Recent research has focused on environmental effects that control tissue functionality and systemic metabolism. However, whether such stimuli affect human thermogenesis and body mass index (BMI) has not been explored. Here we show retrospectively that the presence of brown adipose tissue (BAT) and t...

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Veröffentlicht in:Nature medicine 2018-09, Vol.24 (9), p.1372-1383
Hauptverfasser: Sun, Wenfei, Dong, Hua, Becker, Anton S., Dapito, Dianne H., Modica, Salvatore, Grandl, Gerald, Opitz, Lennart, Efthymiou, Vissarion, Straub, Leon G., Sarker, Gitalee, Balaz, Miroslav, Balazova, Lucia, Perdikari, Aliki, Kiehlmann, Elke, Bacanovic, Sara, Zellweger, Caroline, Peleg-Raibstein, Daria, Pelczar, Pawel, Reik, Wolf, Burger, Irene A., von Meyenn, Ferdinand, Wolfrum, Christian
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Sprache:eng
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