Regulated expression of galectin-1 during T-cell activation involves Lck and Fyn kinases and signaling through MEK1/ERK, p38 MAP kinase and p70 super(S6) kinase

Recent evidence has implicated galectins and their carbohydrate ligands as novel regulators of T-cell homeostasis. Galectin-1 (Gal-1), a member of this family, inhibits clonal expansion, induces apoptosis of antigen-primed T lymphocytes and suppresses the development of T-cell-mediated autoimmune di...

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Veröffentlicht in:	Molecular and cellular biochemistry 2004-12, Vol.267 (1-2), p.177-185
Hauptverfasser:	Fuertes, M B, Molinero, L L, Toscano, MA, Ilarregui, J M, Rubinstein, N, Fainboim, L, Zwirner, N W, Rabinovich, G A
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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