Effects of Prior Effective Therapy on the Efficacy of Daptomycin and Ceftriaxone for the Treatment of Community-Acquired Pneumonia

Objective. We sought to compare daptomycin with ceftriaxone for the treatment of patients with community-acquired pneumonia (CAP). Methods. Two phase-3 randomized, double-blind trials that enrolled adult patients hospitalized with CAP were conducted. Patients received intravenous daptomycin (4 mg/kg...

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Veröffentlicht in:	Clinical infectious diseases 2008-04, Vol.46 (8), p.1142-1151
Hauptverfasser:	Pertel, Peter E., Bernardo, Patricia, Fogarty, Charles, Matthews, Peter, Northland, Rebeca, Benvenuto, Mark, Thorne, Grace M., Luperchio, Steven A., Arbeit, Robert D., Alder, Jeff
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Anti-Bacterial Agents - adverse effects Anti-Bacterial Agents - therapeutic use Antibacterials Articles and Commentaries Ceftriaxone - adverse effects Ceftriaxone - therapeutic use Community-Acquired Infections - drug therapy Community-Acquired Infections - microbiology Community-Acquired Infections - pathology Cubism Daptomycin - adverse effects Daptomycin - therapeutic use Diarrhea - chemically induced Double-Blind Method Drug therapy Effectiveness studies Female Headache - chemically induced Health outcomes Humans Infections Logistic Models Male Medical cures Middle Aged Nausea - chemically induced Pathogens Pharmaceutical preparations Pneumonia Pneumonia - drug therapy Pneumonia - pathology Pneumonia, Ventilator-Associated - drug therapy Pneumonia, Ventilator-Associated - pathology Sepsis - drug therapy Sepsis - pathology Side effects Sputum Staphylococcus aureus Staphylococcus infections State hospitals Streptococcus infections Streptococcus pneumoniae Treatment Outcome
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