Melatonin increases survival of HaCaT keratinocytes by suppressing UV-induced apoptosis

: Melatonin is a potent antioxidant and direct radical scavenger. As keratinocytes represent the major population in the skin and UV light causes damage to these cells, the possible protective effects of melatonin against UV‐induced cell damage in HaCaT keratinocytes were investigated in vitro. Cel...

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Veröffentlicht in:	Journal of pineal research 2006-01, Vol.40 (1), p.18-26
Hauptverfasser:	Fischer, T. W., Zbytek, B., Sayre, R. M., Apostolov, E. O., Basnakian, A. G., Sweatman, T. W., Wortsman, J., Elsner, P., Slominski, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	apoptosis Apoptosis - drug effects Biological and medical sciences cell viability Cells, Cultured clonogenicity Dose-Response Relationship, Radiation Fundamental and applied biological sciences. Psychology Humans In Situ Nick-End Labeling keratinocytes Keratinocytes - drug effects Keratinocytes - metabolism Keratinocytes - radiation effects melatonin Melatonin - pharmacology Thymidine - metabolism Ultraviolet Rays UV light Vertebrates: endocrinology
Online-Zugang:	Volltext
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