Acetyl-L-carnitine prevents total body hydroxyl free radical and uric acid production induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the rat

Acetyl-L-carnitine (ALCAR) is intimately involved in the transport of long chain fatty acids across the inner mitochondrial membrane during oxidative phosphorylation. ALCAR also has been reported to attenuate the occurrence of parkinsonian symptoms associated with 1-methyl-1,2,3,6-tetrahydropyridine...

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Veröffentlicht in:Life sciences (1973) 2004-07, Vol.75 (10), p.1243-1253
Hauptverfasser: Loots, Du Toit, Mienie, Lodewyk J, Bergh, Jacobus J, Van der Schyf, Cornelis J
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Sprache:eng
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