Impairment of bone marrow endothelial progenitor cells in acute graft‐versus‐host disease patients after allotransplant

Summary Graft‐versus‐host disease (GVHD) is a major complication after allogeneic haematopoietic stem cell transplantation (allo‐HSCT) that is frequently associated with bone marrow (BM) suppression, and clinical management is challenging. BM endothelial progenitor cells (EPCs) play crucial roles in...

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Veröffentlicht in:	British journal of haematology 2018-09, Vol.182 (6), p.870-886
Hauptverfasser:	Cao, Xie‐Na, Kong, Yuan, Song, Yang, Shi, Min‐Min, Zhao, Hong‐Yan, Wen, Qi, Lyu, Zhong‐Shi, Duan, Cai‐Wen, Wang, Yu, Xu, Lan‐Ping, Zhang, Xiao‐Hui, Huang, Xiao‐Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	allotransplant Angiogenesis Apoptosis Bone marrow Bone marrow transplantation CD34 antigen DNA damage endothelial progenitor cells Graft-versus-host reaction graft‐versus‐host disease haematopoietic stem cells Hematology Hematopoietic stem cells Impairment Osteoprogenitor cells Reactive oxygen species Stem cell transplantation Thrombopoiesis Transplantation
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