CNTO 95, a fully human anti αv integrin antibody, inhibits cell signaling, migration, invasion, and spontaneous metastasis of human breast cancer cells

CNTO 95 is a fully human monoclonal antibody that recognizes αv integrins. Previous studies have shown that CNTO 95 exhibits both anti-tumor and anti-angiogenic activities (Trikha M et al., Int J Cancer 110:326–335, 2004). In this study we investigated the biological activities of CNTO 95 on breast...

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Veröffentlicht in:	Clinical & experimental metastasis 2008-04, Vol.25 (2), p.139-148
Hauptverfasser:	Chen, Qiming, Manning, Carol D., Millar, Hillary, McCabe, Francis L., Ferrante, Catherine, Sharp, Celia, Shahied-Arruda, Lillian, Doshi, Parul, Nakada, Marian T., Anderson, G. Mark
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical and Life Sciences Biomedicine Cancer Research Hematology Oncology Research Paper Surgical Oncology
Online-Zugang:	Volltext
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