role of TRPV1 receptors in pain evoked by noxious thermal and chemical stimuli

Transient receptor potential receptors (TRP) on primary afferent neurons respond to noxious and/or thermal stimuli. TRPV1 receptors can be activated by noxious heat, acid, capsaicin and resiniferatoxin, leading to burning pain or itch mediated by discharges in C polymodal and Aδ mechano-heat nocicep...

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Veröffentlicht in:	Experimental brain research 2009-06, Vol.196 (1), p.5-11
1. Verfasser:	Willis, William D. Jr
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Animals Biomedical and Life Sciences Biomedicine Heat Hot Temperature Hyperalgesia Kinases Neurology Neurons - physiology Neurosciences Pain Pain - chemically induced Pain - physiopathology Peptides Posterior Horn Cells - physiology Proteins Pruritus - physiopathology Review Spinal cord Spinal Cord - physiopathology Temperature TRPV Cation Channels - metabolism
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