The effects of l -carnitine on the combination of, inhalation anesthetic-induced developmental, neuronal apoptosis in the rat frontal cortex

Abstract The anesthetic gas nitrous oxide (N2 O) and the volatile anesthetic isoflurane (ISO) are commonly used in surgical procedures for human infants and in veterinary and laboratory animal practice to produce loss of consciousness and analgesia. Recent reports indicate that exposure of the devel...

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Veröffentlicht in:	Neuroscience 2008-02, Vol.151 (4), p.1053-1065
Hauptverfasser:	Zou, X, Sadovova, N, Patterson, T.A, Divine, R.L, Hotchkiss, C.E, Ali, S.F, Hanig, J.P, Paule, M.G, Slikker, W, Wang, C
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthetics, Inhalation - toxicity Anesthetics. Neuromuscular blocking agents Animals Animals, Newborn apoptosis Apoptosis - drug effects bcl-2-Associated X Protein - metabolism bcl-X Protein - metabolism Biological and medical sciences Carnitine - pharmacology Caspase 3 - metabolism caspase-3 Dose-Response Relationship, Drug Drug Combinations Fluoresceins Frontal Lobe - cytology Fundamental and applied biological sciences. Psychology isoflurane Isoflurane - toxicity Medical sciences Neural Cell Adhesion Molecule L1 - metabolism Neurology neuronal protection Neurons - cytology Neurons - drug effects Neuropharmacology nitrous oxide Nitrous Oxide - toxicity Organic Chemicals Pharmacology. Drug treatments Rats Rats, Sprague-Dawley Sialic Acids - metabolism Time Factors Vertebrates: nervous system and sense organs Vitamin B Complex - pharmacology
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