Investigation on side-product formation during the synthesis of a lactoferrin-derived lactam-bridged cyclic peptide

Bovine lactoferrin C-lobe is able to prevent both influenza virus hemagglutination and cell infection. In particular, it was demonstrated that the fragment 418 SKHSSLDCVLRP 429 is a potent antiviral peptide. Therefore, we tried to increase the stability of this fragment through side-chain lactam cyc...

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