Activities of naphthoquinones against Aedes aegypti (Linnaeus, 1762) (Diptera: Culicidae), vector of dengue and Biomphalaria glabrata (Say, 1818), intermediate host of Schistosoma mansoni
Larvicidal (against Aedes aegypti Linnaeus, 1762) and molluscicidal (against Biomphalaria glabrata Say, 1818) activities of several natural and synthetic naphthoquinones were measured, with significant results. The best larvicidal compound is 3-bromojuglone, while the better molluscicides are 2-brom...
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creator | Ribeiro, Karlos A.L. de Carvalho, Cenira Monteiro Molina, Maria Teresa Lima, Estelita Pereira López-Montero, Eulogio Reys, José Rui M. de Oliveira, Maria Beatriz Farias Pinto, Antonio Ventura Santana, Antônio Euzébio G. Goulart, Marília O.F. |
description | Larvicidal (against
Aedes aegypti Linnaeus, 1762) and molluscicidal (against
Biomphalaria glabrata Say, 1818) activities of several natural and synthetic naphthoquinones were measured, with significant results. The best larvicidal compound is 3-bromojuglone, while the better molluscicides are 2-bromo- and 3-bromo-5-acetoxy-1,4-naphthoquinones together with the 3-bromo-5-methoxy derivative. The present results reinforce the potential use of substituted hydroxyquinones, their salts and halogenated quinones as very promising compounds against 4th instar larves of
Aedes aegypti, the vector of dengue and against adult snail of
Biomphalaria glabrata. |
doi_str_mv | 10.1016/j.actatropica.2009.02.008 |
format | Article |
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Aedes aegypti Linnaeus, 1762) and molluscicidal (against
Biomphalaria glabrata Say, 1818) activities of several natural and synthetic naphthoquinones were measured, with significant results. The best larvicidal compound is 3-bromojuglone, while the better molluscicides are 2-bromo- and 3-bromo-5-acetoxy-1,4-naphthoquinones together with the 3-bromo-5-methoxy derivative. The present results reinforce the potential use of substituted hydroxyquinones, their salts and halogenated quinones as very promising compounds against 4th instar larves of
Aedes aegypti, the vector of dengue and against adult snail of
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Aedes aegypti Linnaeus, 1762) and molluscicidal (against
Biomphalaria glabrata Say, 1818) activities of several natural and synthetic naphthoquinones were measured, with significant results. The best larvicidal compound is 3-bromojuglone, while the better molluscicides are 2-bromo- and 3-bromo-5-acetoxy-1,4-naphthoquinones together with the 3-bromo-5-methoxy derivative. The present results reinforce the potential use of substituted hydroxyquinones, their salts and halogenated quinones as very promising compounds against 4th instar larves of
Aedes aegypti, the vector of dengue and against adult snail of
Biomphalaria glabrata.</description><subject>Aedes - drug effects</subject><subject>Aedes aegypti</subject><subject>Animals</subject><subject>Antiparasitic Agents - chemical synthesis</subject><subject>Antiparasitic Agents - isolation & purification</subject><subject>Antiparasitic Agents - pharmacology</subject><subject>Arboviroses</subject><subject>Biological and medical sciences</subject><subject>Biomphalaria - drug effects</subject><subject>Biomphalaria glabrata</subject><subject>Bromonaphthoquinones</subject><subject>Culicidae</subject><subject>Dengue</subject><subject>Dengue fevers</subject><subject>Diptera</subject><subject>Diseases caused by trematodes</subject><subject>General aspects</subject><subject>Helminthic diseases</subject><subject>Human viral diseases</subject><subject>Infectious diseases</subject><subject>Insecticides - chemical synthesis</subject><subject>Insecticides - isolation & purification</subject><subject>Insecticides - pharmacology</subject><subject>Isolapachol</subject><subject>Juglone</subject><subject>Lapachol</subject><subject>Larvicidal activity</subject><subject>Medical sciences</subject><subject>Mollusca</subject><subject>Naphthoquinones - chemical synthesis</subject><subject>Naphthoquinones - isolation & purification</subject><subject>Naphthoquinones - pharmacology</subject><subject>Parasitic diseases</subject><subject>Schistosoma mansoni</subject><subject>Schistosomiases</subject><subject>Schistosomiasis</subject><subject>Tropical viral diseases</subject><subject>Viral diseases</subject><issn>0001-706X</issn><issn>1873-6254</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkd2O0zAQhSMEYsvCKyBzAepKm2C7bn64K13-pEpcLEjcWRPHaaZK7KztVOqz8XLrqBVwyZU1o--cGc9JkjeMZoyy_P0hAxUgODuigoxTWmWUZ5SWT5IFK4tVmvO1eJosKKUsLWj-6yp54f0hVrxY8-fJFasEz_OcL5LfGxXwiAG1J7YlBsYudPZhQmNNbMEe0PhANrqZK70_jQHJcofGgJ78LWFFzm_I8g7HoB18INupR4UN6JtbctQqWDfbNtrsJ03ANOQj2mHsoAeHQPY91A4CkOU9nKJZycqoQxO9Bt0gBE06G8dHi3vVoQ_W2wHIAMZbgy-TZy30Xr-6vNfJz8-ffmy_prvvX75tN7tUibIIadkWlSgZF6IuKMCaQVND2zBa1TWtOa-FKjiAqFReVBGpga50WbUFV6WKzdV18u7sO7p4Ge2DHNAr3fdgtJ285DQXueAigtUZVM5673QrR4cDuJNkVM7JyYP8Jzk5JycplzG5qH19GTLV8e9_lZeoIvD2AoBX0LcOjEL_h-NszaqVmLfdnjkdT3JE7aRXqI2K93QxENlY_I91HgFO3L7E</recordid><startdate>20090701</startdate><enddate>20090701</enddate><creator>Ribeiro, Karlos A.L.</creator><creator>de Carvalho, Cenira Monteiro</creator><creator>Molina, Maria Teresa</creator><creator>Lima, Estelita Pereira</creator><creator>López-Montero, Eulogio</creator><creator>Reys, José Rui M.</creator><creator>de Oliveira, Maria Beatriz Farias</creator><creator>Pinto, Antonio Ventura</creator><creator>Santana, Antônio Euzébio G.</creator><creator>Goulart, Marília O.F.</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SS</scope><scope>7U9</scope><scope>C1K</scope><scope>F1W</scope><scope>H94</scope><scope>H95</scope><scope>H97</scope><scope>L.G</scope></search><sort><creationdate>20090701</creationdate><title>Activities of naphthoquinones against Aedes aegypti (Linnaeus, 1762) (Diptera: Culicidae), vector of dengue and Biomphalaria glabrata (Say, 1818), intermediate host of Schistosoma mansoni</title><author>Ribeiro, Karlos A.L. ; de Carvalho, Cenira Monteiro ; Molina, Maria Teresa ; Lima, Estelita Pereira ; López-Montero, Eulogio ; Reys, José Rui M. ; de Oliveira, Maria Beatriz Farias ; Pinto, Antonio Ventura ; Santana, Antônio Euzébio G. ; Goulart, Marília O.F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c487t-8f79481244b70aa51adbafd109bb0b22b4c72aa49c679b70ba03e89f72c8c9c63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Aedes - drug effects</topic><topic>Aedes aegypti</topic><topic>Animals</topic><topic>Antiparasitic Agents - chemical synthesis</topic><topic>Antiparasitic Agents - isolation & purification</topic><topic>Antiparasitic Agents - pharmacology</topic><topic>Arboviroses</topic><topic>Biological and medical sciences</topic><topic>Biomphalaria - drug effects</topic><topic>Biomphalaria glabrata</topic><topic>Bromonaphthoquinones</topic><topic>Culicidae</topic><topic>Dengue</topic><topic>Dengue fevers</topic><topic>Diptera</topic><topic>Diseases caused by trematodes</topic><topic>General aspects</topic><topic>Helminthic diseases</topic><topic>Human viral diseases</topic><topic>Infectious diseases</topic><topic>Insecticides - chemical synthesis</topic><topic>Insecticides - isolation & purification</topic><topic>Insecticides - pharmacology</topic><topic>Isolapachol</topic><topic>Juglone</topic><topic>Lapachol</topic><topic>Larvicidal activity</topic><topic>Medical sciences</topic><topic>Mollusca</topic><topic>Naphthoquinones - chemical synthesis</topic><topic>Naphthoquinones - isolation & purification</topic><topic>Naphthoquinones - pharmacology</topic><topic>Parasitic diseases</topic><topic>Schistosoma mansoni</topic><topic>Schistosomiases</topic><topic>Schistosomiasis</topic><topic>Tropical viral diseases</topic><topic>Viral diseases</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ribeiro, Karlos A.L.</creatorcontrib><creatorcontrib>de Carvalho, Cenira Monteiro</creatorcontrib><creatorcontrib>Molina, Maria Teresa</creatorcontrib><creatorcontrib>Lima, Estelita Pereira</creatorcontrib><creatorcontrib>López-Montero, Eulogio</creatorcontrib><creatorcontrib>Reys, José Rui M.</creatorcontrib><creatorcontrib>de Oliveira, Maria Beatriz Farias</creatorcontrib><creatorcontrib>Pinto, Antonio Ventura</creatorcontrib><creatorcontrib>Santana, Antônio Euzébio G.</creatorcontrib><creatorcontrib>Goulart, Marília O.F.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Virology and AIDS Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 3: Aquatic Pollution & Environmental Quality</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><jtitle>Acta tropica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ribeiro, Karlos A.L.</au><au>de Carvalho, Cenira Monteiro</au><au>Molina, Maria Teresa</au><au>Lima, Estelita Pereira</au><au>López-Montero, Eulogio</au><au>Reys, José Rui M.</au><au>de Oliveira, Maria Beatriz Farias</au><au>Pinto, Antonio Ventura</au><au>Santana, Antônio Euzébio G.</au><au>Goulart, Marília O.F.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Activities of naphthoquinones against Aedes aegypti (Linnaeus, 1762) (Diptera: Culicidae), vector of dengue and Biomphalaria glabrata (Say, 1818), intermediate host of Schistosoma mansoni</atitle><jtitle>Acta tropica</jtitle><addtitle>Acta Trop</addtitle><date>2009-07-01</date><risdate>2009</risdate><volume>111</volume><issue>1</issue><spage>44</spage><epage>50</epage><pages>44-50</pages><issn>0001-706X</issn><eissn>1873-6254</eissn><coden>ACTRAQ</coden><abstract>Larvicidal (against
Aedes aegypti Linnaeus, 1762) and molluscicidal (against
Biomphalaria glabrata Say, 1818) activities of several natural and synthetic naphthoquinones were measured, with significant results. The best larvicidal compound is 3-bromojuglone, while the better molluscicides are 2-bromo- and 3-bromo-5-acetoxy-1,4-naphthoquinones together with the 3-bromo-5-methoxy derivative. The present results reinforce the potential use of substituted hydroxyquinones, their salts and halogenated quinones as very promising compounds against 4th instar larves of
Aedes aegypti, the vector of dengue and against adult snail of
Biomphalaria glabrata.</abstract><cop>Oxford</cop><pub>Elsevier B.V</pub><pmid>19426662</pmid><doi>10.1016/j.actatropica.2009.02.008</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Aedes - drug effects Aedes aegypti Animals Antiparasitic Agents - chemical synthesis Antiparasitic Agents - isolation & purification Antiparasitic Agents - pharmacology Arboviroses Biological and medical sciences Biomphalaria - drug effects Biomphalaria glabrata Bromonaphthoquinones Culicidae Dengue Dengue fevers Diptera Diseases caused by trematodes General aspects Helminthic diseases Human viral diseases Infectious diseases Insecticides - chemical synthesis Insecticides - isolation & purification Insecticides - pharmacology Isolapachol Juglone Lapachol Larvicidal activity Medical sciences Mollusca Naphthoquinones - chemical synthesis Naphthoquinones - isolation & purification Naphthoquinones - pharmacology Parasitic diseases Schistosoma mansoni Schistosomiases Schistosomiasis Tropical viral diseases Viral diseases |
title | Activities of naphthoquinones against Aedes aegypti (Linnaeus, 1762) (Diptera: Culicidae), vector of dengue and Biomphalaria glabrata (Say, 1818), intermediate host of Schistosoma mansoni |
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