New molecular and field evidences for the implication of mycotoxins but not aristolochic acid in human nephropathy and urinary tract tumor

To find out whether ochratoxin A (OTA), citrinin (CIT), aristolochic acids (AA) are etiologic agents of Balkan endemic nephropathy (BEN) or Chinese herbal nephrotoxicity, and associated urinary tract tumor (UTT), we have compared (i) in human kidney cell culture, the DNA adduct formation and persist...

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Veröffentlicht in:	Molecular nutrition & food research 2007-09, Vol.51 (9), p.1131-1146
Hauptverfasser:	Pfohl-Leszkowicz, Annie, Tozlovanu, Mariana, Manderville, Richard, Peraica, Maja, Castegnaro, Marcel, Stefanovic, Vladislav
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Anti-Obesity Agents - analysis Aristolochic acid Aristolochic Acids - analysis Aristolochic Acids - toxicity Aristolochic Acids - urine Balkan Nephropathy - chemically induced Belgium BEN Biological and medical sciences Bulgaria Cell Line Cell Survival - drug effects Citrinin - analysis Citrinin - toxicity Citrinin - urine Croatia DNA Adducts - analysis DNA Adducts - metabolism Female Food Analysis Food industries Food toxicology France Fundamental and applied biological sciences. Psychology Humans Kidney - chemistry Kidney Neoplasms - chemistry Male Middle Aged Mycotoxins - analysis Mycotoxins - toxicity Ochratoxin A Ochratoxins - analysis Ochratoxins - toxicity Ochratoxins - urine Slimming regimen Urinary tract tumor Urologic Neoplasms - chemically induced Urologic Neoplasms - chemistry Yugoslavia
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