Fucoidan from Laminaria cichorioides inhibits AP-1 transactivation and cell transformation in the mouse epidermal JB6 cells

Fucoidan, a sulfated polysaccharide extracted from brown seaweeds, has anticoagulant and antithrombotic activities. Unlike heparine, fucoidan is known to exhibit anticarcinogenic activities. However, the underlying molecular mechanisms of the chemopreventive activities of fucoidan are not understood...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular carcinogenesis 2008-08, Vol.47 (8), p.629-637
Hauptverfasser:	Lee, Na Yeon, Ermakova, Svetlana P., Choi, Hoo-Kyun, Kusaykin, Michail I., Shevchenko, Natalya M., Zvyagintseva, Tatyana N., Choi, Hong Seok
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals AP-1 c-fos c-jun Cell Adhesion Cell Line cell transformation Cell Transformation, Neoplastic EGFR Epidermal Cells Epidermal Growth Factor - metabolism fucoidan Laminaria - metabolism Laminaria cichorioides MAP Kinase Signaling System Mice Phosphorylation Polysaccharides - chemistry Tetradecanoylphorbol Acetate Transcription Factor AP-1 - metabolism Transcriptional Activation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!