Early cortical damage in rat somatosensory cortex alters acoustic feature representation in primary auditory cortex

Abstract Early postnatal freeze-lesions to the cortical plate result in malformations resembling human microgyria. Microgyria in primary somatosensory cortex (S1) of rats are associated with a reduced behavioral detection of rapid auditory transitions and the loss of large cells in the thalamic nucl...

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Veröffentlicht in:	Neuroscience 2007-12, Vol.150 (4), p.970-983
Hauptverfasser:	Escabí, M.A, Higgins, N.C, Galaburda, A.M, Rosen, G.D, Read, H.L
Format:	Artikel
Sprache:	eng
Schlagworte:	Acoustic Stimulation - methods Acoustics Animals Animals, Newborn auditory Auditory Cortex - physiopathology Auditory Perception - physiology Biological and medical sciences Brain Injuries - pathology Brain Mapping Critical Period (Psychology) Dose-Response Relationship, Radiation Ear and associated structures. Auditory pathways and centers. Hearing. Vocal organ. Phonation. Sound production. Echolocation Evoked Potentials, Auditory - physiology Female Functional Laterality Fundamental and applied biological sciences. Psychology Male microgyria Neurology perinatal plasticity Pregnancy Rats Rats, Wistar Reaction Time Somatosensory Cortex - injuries Somatosensory Cortex - physiopathology Somesthesis and somesthetic pathways (proprioception, exteroception, nociception) interoception electrolocation. Sensory receptors spectral temporal Vertebrates: nervous system and sense organs
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