Subcellular localization and expression of E-cadherin and SNAIL are relevant since early stages of oral carcinogenesis

The biological process of epithelial-to-mesenchymal transition (EMT) has been studied in oral squamous cell carcinoma (OSCC) metastasis, but it is rarely evaluated at several stages of oral carcinogenesis. This study aimed to analyze the presence of SNAIL and E-cadherin proteins, markers of EMT, in...

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Veröffentlicht in:	Pathology, research and practice research and practice, 2018-08, Vol.214 (8), p.1185-1191
Hauptverfasser:	Lopes, Nathália Martins, Xavier, Flávia Caló Aquino, Ortiz, Rafael Carneiro, Amôr, Nádia Ghinelli, Garlet, Gustavo Pompermaier, Lara, Vanessa Soares, Batista, Aline Carvalho, Costa, Nádia Lago, Rodini, Camila Oliveira
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antigens, CD Cadherins - metabolism Carcinogenesis - metabolism Carcinogenesis - pathology Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - pathology Cell Nucleus - metabolism Cytoplasm - metabolism Epithelial dysplasia Epithelial-Mesenchymal Transition - physiology Epithelial-To-Mesenchymal transition Female Head and Neck Neoplasms - metabolism Head and Neck Neoplasms - pathology Humans Male Middle Aged Mouth Neoplasms - metabolism Mouth Neoplasms - pathology Oral carcinogenesis Oral leukoplakia Oral squamous cell carcinoma Precancerous Conditions - metabolism Precancerous Conditions - pathology Snail Family Transcription Factors - metabolism Squamous Cell Carcinoma of Head and Neck
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