Toxicity study of maternal transfer of polychlorinated biphenyls and diethyl phthalate to 21-day-old male and female weanling pups of Wistar rats

Polychlorinated biphenyls (PCBs) are environmental pollutants known to act as xenoestrogens. PCBs and diethylphthalate (DEP) are ubiquitous environmental pollutants because both are used as plasticizers and in various other industrial applications. Therefore, a study was undertaken to evaluate the i...

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Veröffentlicht in:	Ecotoxicology and environmental safety 2007-09, Vol.68 (1), p.118-125
Hauptverfasser:	Pereira, Contzen, Rao, C. Vaman
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid Phosphatase - metabolism Alkaline Phosphatase - metabolism Animal, plant and microbial ecology Animals Applied ecology Biological and medical sciences Clophen A60 Diethyl phthalate (DEP) Drug Synergism Drug Therapy, Combination Ecotoxicology, biological effects of pollution Environmental Exposure - adverse effects Environmental Pollutants - toxicity Enzymes Fatty Liver - chemically induced Fatty Liver - pathology Female Fundamental and applied biological sciences. Psychology General aspects Histology L-Lactate Dehydrogenase - metabolism Liver Liver - drug effects Liver - enzymology Liver - pathology Male Organ Size - drug effects Phthalic Acids - pharmacokinetics Phthalic Acids - toxicity Polychlorinated biphenyls (PCBs) Polychlorinated Biphenyls - pharmacokinetics Polychlorinated Biphenyls - toxicity Pregnancy Prenatal Exposure Delayed Effects - chemically induced Prenatal Exposure Delayed Effects - pathology Rats Rats, Wistar Reproduction - drug effects Serum Toxicity Tests
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