Pyridine nucleotides regulate the superoxide anion flash upon permeabilization of mitochondrial membranes: An MCLA-based study

The permeabilization of mitochondrial membranes via permeability transition pore opening or by the pore-forming peptide alamethicin causes a flash of superoxide anion (SA) and hydrogen peroxide production and the inhibition of matrix aconitase. It was shown using the SA probe 3,7-dihydro-2-methyl-6-...

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Veröffentlicht in:	Free radical biology & medicine 2018-08, Vol.124, p.473-483
Hauptverfasser:	Kharechkina, Ekaterina S., Nikiforova, Anna B., Kruglov, Alexey G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenodoxin reductase Inner mitochondrial membrane NADH NADPH Permeability transition pore Redox potential Superoxide flash
Online-Zugang:	Volltext
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