Targeting the Myofibroblast in Pulmonary Fibrosis

Unbiased genomewide association studies and careful genetic studies conducted in families with high rates of pulmonary fibrosis have identified mutations in genes largely expressed in the lung epithelium (MUC5B and SFTPC) as important risk factors for the development of idiopathic pulmonary fibrosis...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	American journal of respiratory and critical care medicine 2018-10, Vol.198 (7), p.834-835
Hauptverfasser:	Misharin, Alexander V, Budinger, G R Scott
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Fibroblasts Gene expression Humans Idiopathic Pulmonary Fibrosis Investigations Myofibroblasts Phosphatase Phosphorylation Protein Tyrosine Phosphatases Proteins Pulmonary fibrosis Tumor necrosis factor-TNF
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!