Histone modifications induced by a family of bacterial toxins

Upon infection, pathogens reprogram host gene expression. In eukaryotic cells, genetic reprogramming is induced by the concerted activation/repression of transcription factors and various histone modifications that control DNA accessibility in chromatin. We report here that the bacterial pathogen Li...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2007-08, Vol.104 (33), p.13467-13472
Hauptverfasser:	Hamon, Mélanie Anne, Batsché, Eric, Régnault, Béatrice, Tham, To Nam, Seveau, Stéphanie, Muchardt, Christian, Cossart, Pascale
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Bacteria Bacterial proteins Bacterial Toxins - chemistry Biological Sciences Cell membranes Cellular Biology Chromatin Clostridium perfringens Epigenetics Eukaryotes Gene expression Gene expression regulation Genes HeLa Cells Histones Histones - chemistry Humans Infections Life Sciences Listeria monocytogenes Listeria monocytogenes - physiology Pathogens Phosphorylation Reverse Transcriptase Polymerase Chain Reaction Streptococcus pneumoniae Toxins Transcription, Genetic
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