Regulation of glutathione transferase P: A tumor marker of hepatocarcinogenesis

Placental glutathione transferase (GST-P) is specifically expressed during rat haptocarcinogenesis, and has been used as a reliable tumor marker for experimental hepatocarcinogenesis in the rat. The regulation of this tumor marker gene may be associated with the process of carcinogeneisis. By elucid...

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Veröffentlicht in:	Biochemical and biophysical research communications 2007-06, Vol.357 (3), p.575-578
Hauptverfasser:	Sakai, Masaharu, Muramatsu, Masami
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals C/EBPα CCAAT-Enhancer-Binding Protein-alpha - metabolism Gene Expression Regulation, Enzymologic Glutathione S-Transferase pi - genetics Glutathione S-Transferase pi - metabolism Glutathione transferase P Haptoma Humans Liver - enzymology Liver Neoplasms - enzymology Liver Neoplasms - genetics Liver Neoplasms - pathology Models, Biological Nrf2 Precancerous Conditions - enzymology Precancerous Conditions - genetics Precancerous Conditions - pathology Protein Binding Transcriptional control Tumor marker
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