The MTHFR C677T and ΔDNMT3B C‐149T polymorphisms confer different risks for right‐ and left‐sided colorectal cancer

Etiological risk factors for proximal (right‐sided) colon cancers may be different to those of distal colon and rectal (left‐sided) cancers if these tumors develop along distinct pathways. The CpG Island Methylator Phenotype (CIMP+) occurs in approximately 15% of colorectal cancers (CRC) and predomi...

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Veröffentlicht in:International journal of cancer 2009-07, Vol.125 (1), p.84-90
Hauptverfasser: Iacopetta, Barry, Heyworth, Jane, Girschik, Jennifer, Grieu, Fabienne, Clayforth, Cassandra, Fritschi, Lin
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Sprache:eng
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