Long-acting injectable antipsychotics for the treatment of schizophrenia in Spain

Antipsychotics are an essential component in the treatment of schizophrenia. Long-acting injectable formulations (LAI) arose to improve adherence with the associated potential of reducing the risk of relapse. The objective of this article is to analyze the use of LAI antipsychotics in Spain, which i...

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Veröffentlicht in:Revista de psiquiatria y salud mental 2019-04, Vol.12 (2), p.92-105
Hauptverfasser: Arango, Celso, Baeza, Inmaculada, Bernardo, Miquel, Cañas, Fernando, de Dios, Consuelo, Díaz-Marsá, Marina, García-Portilla, María Paz, Gutiérrez-Rojas, Luis, Olivares, José Manuel, Rico-Villademoros, Fernando, Rodríguez-Jiménez, Roberto, Sánchez-Morla, Eva María, Segarra, Rafael, Crespo-Facorro, Benedicto
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container_issue 2
container_start_page 92
container_title Revista de psiquiatria y salud mental
container_volume 12
creator Arango, Celso
Baeza, Inmaculada
Bernardo, Miquel
Cañas, Fernando
de Dios, Consuelo
Díaz-Marsá, Marina
García-Portilla, María Paz
Gutiérrez-Rojas, Luis
Olivares, José Manuel
Rico-Villademoros, Fernando
Rodríguez-Jiménez, Roberto
Sánchez-Morla, Eva María
Segarra, Rafael
Crespo-Facorro, Benedicto
description Antipsychotics are an essential component in the treatment of schizophrenia. Long-acting injectable formulations (LAI) arose to improve adherence with the associated potential of reducing the risk of relapse. The objective of this article is to analyze the use of LAI antipsychotics in Spain, which is similar to other European countries but with a predominance of the use of second generation LAI, to discuss the possible causes of prescribing differences with respect to other countries (including organizational aspects, attitudes of psychiatrists, patients and family members, and clinical practice guidelines), and to discuss their use in acute psychiatric units, first episode, and in children and adolescents. In our view, while it is necessary to increase existing evidence regarding the advantages of LAI antipsychotics and the differentiation between LAI antipsychotics currently available, their use will likely continue to grow driven by clinical experience.
doi_str_mv 10.1016/j.rpsm.2018.03.006
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subjects Antipsychotic Agents - administration & dosage
Antipsychotic Agents - therapeutic use
Delayed-Action Preparations
Drug Utilization - trends
Humans
Injections, Intramuscular
Practice Patterns, Physicians' - trends
Schizophrenia - drug therapy
Spain
Treatment Outcome
title Long-acting injectable antipsychotics for the treatment of schizophrenia in Spain
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