FGF9 modulates Schwann cell myelination in developing nerves and induces a pro‐inflammatory environment during injury

Myelin sheath is critical for the proper functioning of the peripheral nervous system (PNS), which allows the effective conduction of nerve impulses. Fibroblast growth factor 9 (FGF9) is an autocrine and paracrine protein in the fibroblast growth factor family that regulates cell differentiation and...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of cellular biochemistry 2018-11, Vol.119 (10), p.8643-8658
Hauptverfasser:	Deng, Binbin, Lv, Wenjing, Duan, Weisong, Liu, Yakun, Li, Zhongyao, Song, Xueqing, Cui, Can, Qi, Xiaoming, Wang, Xiaoxiao, Li, Chunyan
Format:	Artikel
Sprache:	eng
Schlagworte:	Ablation Animals Antigens, CD - metabolism Antigens, Differentiation, Myelomonocytic - metabolism Apoptosis - physiology Autocrine signalling Axons - metabolism B7-2 Antigen - metabolism Behavior, Animal - physiology CD86 antigen Cell differentiation Deactivation Degeneration Differentiation (biology) Extracellular signal-regulated kinase extracellular‐regulated kinases 1/2 Fibroblast growth factor 9 Fibroblast Growth Factor 9 - genetics Fibroblast Growth Factor 9 - metabolism Fibroblast growth factor receptor 9 Fibroblasts Gene expression Gene Knockout Techniques Genes Growth factors Inactivation Inflammation Inflammation - metabolism injury Interleukin-1beta - metabolism Kinases MAP Kinase Signaling System Mice Mice, Inbred C57BL Mice, Knockout Morphology Mutation Myelin Myelin Sheath - metabolism Myelination Nervous system Neurogenesis - physiology Paracrine signalling Peripheral Nerve Injuries - metabolism Peripheral nerves Peripheral nervous system Peripheral Nervous System - metabolism Proteins Rodents Schwann cell Schwann Cells - metabolism Sciatic Nerve - growth & development Sheaths Statistics, Nonparametric Superoxide dismutase Superoxide Dismutase - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!