Differential clinical features of patients with clinically amyopathic dermatomyositis who have circulating anti-MDA5 autoantibodies with or without myositis-associated autoantibodies

Anti-melanoma differentiation-associated gene 5 (MDA5) autoantibodies have been identified as myositis-specific autoantibodies that are often associated with clinically amyopathic dermatomyositis (CADM) and a poor prognosis due to rapidly progressive interstitial lung disease (RP-ILD) in East Asian...

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Veröffentlicht in:	Respiratory medicine 2018-07, Vol.140, p.1-5
Hauptverfasser:	Yamaguchi, Koichi, Yamaguchi, Aya, Kashiwagi, Chiharu, Sawada, Yuri, Taguchi, Kohei, Umetsu, Kazue, Oshima, Kazuma, Uchida, Megumi, Suzuki, Masafumi, Kono, Shunichi, Takemura, Masao, Masubuchi, Hiroaki, Kitahara, Shinsuke, Hara, Kenichiro, Maeno, Toshitaka, Motegi, Sei-ichiro, Muro, Yoshinao, Sakairi, Toru, Hisada, Takeshi, Kurabayashi, Masahiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Anti-MDA5 autoantibody Antibodies Antinuclear antibodies Arthritis Autoantibodies Autoantibodies - blood Biomarkers Biomarkers - blood Cardiolipin Citrulline Clinically amyopathic dermatomyositis Coexistence Computed tomography Connective tissue diseases Connective tissues Corticoids Corticosteroids Dermatomyositis Dermatomyositis - diagnosis Dermatomyositis - drug therapy Dermatomyositis - immunology Disease Progression Enzymes Female Glucocorticoids - therapeutic use Humans Immunoassay Immunoglobulins Immunosuppressive agents Immunosuppressive Agents - therapeutic use Inflammatory diseases Interferon-Induced Helicase, IFIH1 - immunology Kaplan-Meier Estimate Laboratories Laboratory tests Lung diseases Lung Diseases, Interstitial - diagnosis Lung Diseases, Interstitial - drug therapy Lung Diseases, Interstitial - immunology Male Medical imaging Medical prognosis Melanoma Middle Aged Musculoskeletal diseases Myositis Myositis - immunology Myositis-associated antibody Patients Phenotypes Prognosis Rapidly progressive interstitial lung disease Raynaud disease Retrospective Studies Rheumatoid arthritis Sjogren's syndrome Therapy Tomography, X-Ray Computed
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