Evaluation of the Protective Effects of Alkaloids Isolated from the Hooks and Stems of Uncaria sinensis on Glutamate-induced Neuronal Death in Cultured Cerebellar Granule Cells from Rats

We have previously shown that an aqueous extract of the hooks and stems of Uncaria sinensis (Oliv.) Havil., Uncariae Uncus Cum Ramulusis, protects against glutamate‐induced neuronal death in cultured cerebellar granule cells by inhibition of Ca2+ influx. Because it is not known which components of U...

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Veröffentlicht in:	Journal of pharmacy and pharmacology 1999-06, Vol.51 (6), p.715-722
Hauptverfasser:	SHIMADA, YUTAKA, GOTO, HIROZO, ITOH, TAKASHI, SAKAKIBARA, IWAO, KUBO, MASAYOSHI, SASAKI, HIROSHI, TERASAWA, KATSUTOSHI
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaloids - pharmacology Animals Biological and medical sciences Calcium - metabolism Cell Death - drug effects Cells, Cultured Cerebellum - drug effects Dose-Response Relationship, Drug General pharmacology Glutamic Acid - toxicity Medical sciences Neuroprotective Agents - pharmacology Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plants, Medicinal Rats Rats, Wistar
Online-Zugang:	Volltext
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