Altered gene expression in lymphoblastoid cell lines after subculture

Lymphoblastoid cell lines (LCLs) are nearly immortalized B lymphocytes that are used as long-lasting supply of human cells for studies on gene expression analyses. However, studies on the stability of the cellular features of LCLs are scarce. To address this issue, we measured gene expression in LCL...

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Veröffentlicht in:	In vitro cellular & developmental biology. Animal 2018-08, Vol.54 (7), p.523-527
Hauptverfasser:	Toritsuka, Michihiro, Makinodan, Manabu, Yamauchi, Takahira, Yamashita, Yasunori, Ikawa, Daisuke, Komori, Takashi, Kimoto, Sohei, Hamano-Iwasa, Kaori, Matsuzaki, Hideo, Kishimoto, Toshifumi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Genetics and Genomics Autism Biomedical and Life Sciences Biotechnology Cell Biology Cell Culture Cell Culture Techniques - methods Cell Line CELLULAR PATHOLOGY/VIROLOGY Cytokines Cytokines - genetics Cytokines - metabolism Dehydrogenases Developmental Biology DNA methylation Epigenetics Gene expression Gene Expression Regulation Genomes Glyceraldehyde-3-phosphate dehydrogenase Humans Laboratories Life Sciences Lymphoblastoid cell lines Lymphocytes Lymphocytes - metabolism Lymphocytes B Psychiatry Reference Standards Schizophrenia Stability analysis Stem Cells Studies Subculture Systematic review Tumor necrosis factor-TNF Variance analysis
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