Establishment and characterization of novel patient-derived osteosarcoma xenograft and cell line

Osteosarcoma is an aggressive mesenchymal malignancy of the bone. Patient-derived models are essential tools for elucidating the molecular mechanisms associated with poor prognosis and the development of novel anticancer drugs. This study described the establishment of a patient-derived cancer model...

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Veröffentlicht in:	In vitro cellular & developmental biology. Animal 2018-08, Vol.54 (7), p.528-536
Hauptverfasser:	Kito, Fusako, Oyama, Rieko, Sakumoto, Marimu, Takahashi, Mami, Shiozawa, Kumiko, Qiao, Zhiwei, Sakamoto, Hiromi, Hirose, Takeshi, Setsu, Nokitaka, Yoshida, Akihiko, Kawai, Akira, Kondo, Tadashi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Genetics and Genomics Antineoplastic drugs Antitumor agents Biocompatibility Biomedical and Life Sciences Bone cancer Cancer therapies Cell Biology Cell Culture Chemotherapy Developmental Biology Drug development Drugs Epidemiology ESTABLISHMENT OF CELL LINES Experiments Genes Genomes Genomics Histology Immunodeficiency Immunosuppressive agents Invasiveness Life Sciences Malignancy Mass spectrometry Mass spectroscopy Medical prognosis Mesenchyme Metastasis Mice Molecular modelling Osteosarcoma Patients Proteomes Proteomics RNA polymerase Sarcoma Skin Spheroids Stem Cells Tissue culture Tissues Transplantation Transplants & implants Tumors Xenografts Xenotransplantation
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