Extracellular Matrix Metalloproteinase Inducer (CD147) Is a Novel Receptor on Platelets, Activates Platelets, and Augments Nuclear Factor κB-Dependent Inflammation in Monocytes

In atherosclerosis, circulating platelets interact with endothelial cells and monocytes, leading to cell activation and enhanced recruitment of leukocytes into the vascular wall. The invasion of monocytes is accompanied by overexpression of matrix metalloproteinases (MMPs), which are thought to prom...

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Veröffentlicht in:Circulation research 2008-02, Vol.102 (3), p.302-309
Hauptverfasser: Schmidt, Roland, Bültmann, Andreas, Fischel, Sina, Gillitzer, Angelika, Cullen, Paul, Walch, Axel, Jost, Philipp, Ungerer, Martin, Tolley, Neal D, Lindemann, Stephan, Gawaz, Meinrad, Schömig, Albert, May, Andreas E
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Sprache:eng
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