HLA-DQ-binding peptide motifs. I. Comparative binding analysis of type II collagen-derived peptides to DR and DQ molecules of rheumatoid arthritis-susceptible and non-susceptible haplotypes

The frequency of the HLA-DR4-DQ4 haplotype (DRB1*0405–DQA1*0302–DQB1*0401) is significantly increased in Japanese patients with rheumatoid arthritis (RA) and DRB1*0405-binding peptide motifs were identified in our previous studies. To clarify the DQ4-binding peptide motifs, the primary structure of...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	International immunology 1996-05, Vol.8 (5), p.757-764
Hauptverfasser:	Matsushita, Sho, Nishi, Tohru, Oiso, Masatake, Yamaoka, Kazuyoshi, Yone, Kenji, Kanai, Takayuki, Nishimura, Yasuharu
Format:	Artikel
Sprache:	eng
Schlagworte:	autoimmunity DQ4 DQB10401 DR4 DRB10405 HLA MHC peptide display library peptide motifs rheumatoid arthritis type II collagen
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!