Prevalence and topographical characteristics of keratoconus in patients with refractive errors in the Egyptian delta
Purpose To study the prevalence of keratoconus (KC) and the topographical characteristics of the affected corneas in patients with refractive errors who were seeking refractive surgery in the Egyptian delta. Methods A retrospective study covering four and half years (Jan 2012–June 2016) where the to...
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| Veröffentlicht in: | International ophthalmology 2019-07, Vol.39 (7), p.1459-1465 |
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| creator | Elbedewy, Hazem A. Wasfy, Tamer E. Soliman, Shaimaa S. Sabry, Moataz M. Awara, Amr M. El Emam, Sharif Y. Shafik, Heba M. Alam, Mostafa R. |
| description | Purpose
To study the prevalence of keratoconus (KC) and the topographical characteristics of the affected corneas in patients with refractive errors who were seeking refractive surgery in the Egyptian delta.
Methods
A retrospective study covering four and half years (Jan 2012–June 2016) where the topographical data of 8124 participants were obtained from the records of a refractive center in the Nile delta region, Egypt. The diagnosis of KC was based on the Holladay criteria in one or both eyes, using the Pentacam scans, whereas grading of KC was based on the Amsler-Krumeich classification.
Results
The prevalence of KC was 1.12% (91/8124 participants) with 95% confidence interval 0.91–1.3. Of all the affected cases, 5 cases (5.5%) had unilateral, and the other 86 cases (94.5%) had bilateral KC. The affected and unaffected subjects did not show any significant difference regarding gender. Sixty-eight (38.4%) eyes had stage 1 KC, 53 eyes (29.9%) had stage 2, 27 eyes (15.3%) had stage 3, and 29 eyes (16.4%) had stage 4 KC. It was most prevalent (1.2%) among cases with astigmatism (
P
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| doi_str_mv | 10.1007/s10792-018-0965-4 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2059044511</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2058844131</sourcerecordid><originalsourceid>FETCH-LOGICAL-c372t-2167614c9c0e858b76b007d6add747e61de1137cd0ff0bd2c1bb35ad5da57d973</originalsourceid><addsrcrecordid>eNp1kU2LFDEQhoMo7jj6A7xIwIuX1kq60-kcZVk_YEEPeg7ppHoma0_SJumV_femnVVB8BSoPPVWFQ8hzxm8ZgDyTWYgFW-ADQ2oXjTdA7JjQrYN71t4SHbAalFIYBfkSc43AKCk6h-TC65UO7SM70j5nPDWzBgsUhMcLXGJh2SWo7dmpvZokrEFk8_F20zjRL9hMiXaGNZMfaCLKR5DyfSHL0eacNp4f4sUU4rpF1KOSK8Od0vxJlCHczFPyaPJzBmf3b978vXd1ZfLD831p_cfL99eN7aVvDSc9bJnnVUWcBDDKPuxXu1645zsJPbMIWOttA6mCUbHLRvHVhgnnBHSKdnuyatz7pLi9xVz0SefLc6zCRjXrDkIBV0nasqevPwHvYlrCnW7jRqGrmPtRrEzZVPMuV6rl-RPJt1pBnpTos9KdFWiNyW6qz0v7pPX8YTuT8dvBxXgZyDXr3DA9Hf0_1N_ApNTmGw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2058844131</pqid></control><display><type>article</type><title>Prevalence and topographical characteristics of keratoconus in patients with refractive errors in the Egyptian delta</title><source>MEDLINE</source><source>Springer Journals</source><creator>Elbedewy, Hazem A. ; Wasfy, Tamer E. ; Soliman, Shaimaa S. ; Sabry, Moataz M. ; Awara, Amr M. ; El Emam, Sharif Y. ; Shafik, Heba M. ; Alam, Mostafa R.</creator><creatorcontrib>Elbedewy, Hazem A. ; Wasfy, Tamer E. ; Soliman, Shaimaa S. ; Sabry, Moataz M. ; Awara, Amr M. ; El Emam, Sharif Y. ; Shafik, Heba M. ; Alam, Mostafa R.</creatorcontrib><description>Purpose
To study the prevalence of keratoconus (KC) and the topographical characteristics of the affected corneas in patients with refractive errors who were seeking refractive surgery in the Egyptian delta.
Methods
A retrospective study covering four and half years (Jan 2012–June 2016) where the topographical data of 8124 participants were obtained from the records of a refractive center in the Nile delta region, Egypt. The diagnosis of KC was based on the Holladay criteria in one or both eyes, using the Pentacam scans, whereas grading of KC was based on the Amsler-Krumeich classification.
Results
The prevalence of KC was 1.12% (91/8124 participants) with 95% confidence interval 0.91–1.3. Of all the affected cases, 5 cases (5.5%) had unilateral, and the other 86 cases (94.5%) had bilateral KC. The affected and unaffected subjects did not show any significant difference regarding gender. Sixty-eight (38.4%) eyes had stage 1 KC, 53 eyes (29.9%) had stage 2, 27 eyes (15.3%) had stage 3, and 29 eyes (16.4%) had stage 4 KC. It was most prevalent (1.2%) among cases with astigmatism (
P
< 0.001).
Conclusion
Keratoconus was found in 1.12% of patients seeking refractive surgery, with no gender preference. Most cases had bilateral affection. Astigmatism was the most common refractive error to be associated with keratoconus.</description><identifier>ISSN: 0165-5701</identifier><identifier>EISSN: 1573-2630</identifier><identifier>DOI: 10.1007/s10792-018-0965-4</identifier><identifier>PMID: 29938312</identifier><language>eng</language><publisher>Dordrecht: Springer Netherlands</publisher><subject>Adult ; Astigmatism ; Confidence intervals ; Cornea - pathology ; Corneal Topography - methods ; Egypt - epidemiology ; Evaluation ; Eye ; Female ; Follow-Up Studies ; Humans ; Keratoconus ; Keratoconus - complications ; Keratoconus - diagnosis ; Keratoconus - epidemiology ; Male ; Medicine ; Medicine & Public Health ; Ophthalmology ; Original Paper ; Patients ; Population Surveillance ; Prevalence ; Refraction, Ocular ; Refractive Errors - complications ; Refractive Errors - diagnosis ; Refractive Errors - epidemiology ; Retrospective Studies ; Surgery</subject><ispartof>International ophthalmology, 2019-07, Vol.39 (7), p.1459-1465</ispartof><rights>Springer Nature B.V. 2018</rights><rights>International Ophthalmology is a copyright of Springer, (2018). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-2167614c9c0e858b76b007d6add747e61de1137cd0ff0bd2c1bb35ad5da57d973</citedby><cites>FETCH-LOGICAL-c372t-2167614c9c0e858b76b007d6add747e61de1137cd0ff0bd2c1bb35ad5da57d973</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10792-018-0965-4$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10792-018-0965-4$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29938312$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Elbedewy, Hazem A.</creatorcontrib><creatorcontrib>Wasfy, Tamer E.</creatorcontrib><creatorcontrib>Soliman, Shaimaa S.</creatorcontrib><creatorcontrib>Sabry, Moataz M.</creatorcontrib><creatorcontrib>Awara, Amr M.</creatorcontrib><creatorcontrib>El Emam, Sharif Y.</creatorcontrib><creatorcontrib>Shafik, Heba M.</creatorcontrib><creatorcontrib>Alam, Mostafa R.</creatorcontrib><title>Prevalence and topographical characteristics of keratoconus in patients with refractive errors in the Egyptian delta</title><title>International ophthalmology</title><addtitle>Int Ophthalmol</addtitle><addtitle>Int Ophthalmol</addtitle><description>Purpose
To study the prevalence of keratoconus (KC) and the topographical characteristics of the affected corneas in patients with refractive errors who were seeking refractive surgery in the Egyptian delta.
Methods
A retrospective study covering four and half years (Jan 2012–June 2016) where the topographical data of 8124 participants were obtained from the records of a refractive center in the Nile delta region, Egypt. The diagnosis of KC was based on the Holladay criteria in one or both eyes, using the Pentacam scans, whereas grading of KC was based on the Amsler-Krumeich classification.
Results
The prevalence of KC was 1.12% (91/8124 participants) with 95% confidence interval 0.91–1.3. Of all the affected cases, 5 cases (5.5%) had unilateral, and the other 86 cases (94.5%) had bilateral KC. The affected and unaffected subjects did not show any significant difference regarding gender. Sixty-eight (38.4%) eyes had stage 1 KC, 53 eyes (29.9%) had stage 2, 27 eyes (15.3%) had stage 3, and 29 eyes (16.4%) had stage 4 KC. It was most prevalent (1.2%) among cases with astigmatism (
P
< 0.001).
Conclusion
Keratoconus was found in 1.12% of patients seeking refractive surgery, with no gender preference. Most cases had bilateral affection. Astigmatism was the most common refractive error to be associated with keratoconus.</description><subject>Adult</subject><subject>Astigmatism</subject><subject>Confidence intervals</subject><subject>Cornea - pathology</subject><subject>Corneal Topography - methods</subject><subject>Egypt - epidemiology</subject><subject>Evaluation</subject><subject>Eye</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Keratoconus</subject><subject>Keratoconus - complications</subject><subject>Keratoconus - diagnosis</subject><subject>Keratoconus - epidemiology</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Ophthalmology</subject><subject>Original Paper</subject><subject>Patients</subject><subject>Population Surveillance</subject><subject>Prevalence</subject><subject>Refraction, Ocular</subject><subject>Refractive Errors - complications</subject><subject>Refractive Errors - diagnosis</subject><subject>Refractive Errors - epidemiology</subject><subject>Retrospective Studies</subject><subject>Surgery</subject><issn>0165-5701</issn><issn>1573-2630</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kU2LFDEQhoMo7jj6A7xIwIuX1kq60-kcZVk_YEEPeg7ppHoma0_SJumV_femnVVB8BSoPPVWFQ8hzxm8ZgDyTWYgFW-ADQ2oXjTdA7JjQrYN71t4SHbAalFIYBfkSc43AKCk6h-TC65UO7SM70j5nPDWzBgsUhMcLXGJh2SWo7dmpvZokrEFk8_F20zjRL9hMiXaGNZMfaCLKR5DyfSHL0eacNp4f4sUU4rpF1KOSK8Od0vxJlCHczFPyaPJzBmf3b978vXd1ZfLD831p_cfL99eN7aVvDSc9bJnnVUWcBDDKPuxXu1645zsJPbMIWOttA6mCUbHLRvHVhgnnBHSKdnuyatz7pLi9xVz0SefLc6zCRjXrDkIBV0nasqevPwHvYlrCnW7jRqGrmPtRrEzZVPMuV6rl-RPJt1pBnpTos9KdFWiNyW6qz0v7pPX8YTuT8dvBxXgZyDXr3DA9Hf0_1N_ApNTmGw</recordid><startdate>20190701</startdate><enddate>20190701</enddate><creator>Elbedewy, Hazem A.</creator><creator>Wasfy, Tamer E.</creator><creator>Soliman, Shaimaa S.</creator><creator>Sabry, Moataz M.</creator><creator>Awara, Amr M.</creator><creator>El Emam, Sharif Y.</creator><creator>Shafik, Heba M.</creator><creator>Alam, Mostafa R.</creator><general>Springer Netherlands</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7T7</scope><scope>7TK</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20190701</creationdate><title>Prevalence and topographical characteristics of keratoconus in patients with refractive errors in the Egyptian delta</title><author>Elbedewy, Hazem A. ; Wasfy, Tamer E. ; Soliman, Shaimaa S. ; Sabry, Moataz M. ; Awara, Amr M. ; El Emam, Sharif Y. ; Shafik, Heba M. ; Alam, Mostafa R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c372t-2167614c9c0e858b76b007d6add747e61de1137cd0ff0bd2c1bb35ad5da57d973</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Adult</topic><topic>Astigmatism</topic><topic>Confidence intervals</topic><topic>Cornea - pathology</topic><topic>Corneal Topography - methods</topic><topic>Egypt - epidemiology</topic><topic>Evaluation</topic><topic>Eye</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Keratoconus</topic><topic>Keratoconus - complications</topic><topic>Keratoconus - diagnosis</topic><topic>Keratoconus - epidemiology</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Ophthalmology</topic><topic>Original Paper</topic><topic>Patients</topic><topic>Population Surveillance</topic><topic>Prevalence</topic><topic>Refraction, Ocular</topic><topic>Refractive Errors - complications</topic><topic>Refractive Errors - diagnosis</topic><topic>Refractive Errors - epidemiology</topic><topic>Retrospective Studies</topic><topic>Surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Elbedewy, Hazem A.</creatorcontrib><creatorcontrib>Wasfy, Tamer E.</creatorcontrib><creatorcontrib>Soliman, Shaimaa S.</creatorcontrib><creatorcontrib>Sabry, Moataz M.</creatorcontrib><creatorcontrib>Awara, Amr M.</creatorcontrib><creatorcontrib>El Emam, Sharif Y.</creatorcontrib><creatorcontrib>Shafik, Heba M.</creatorcontrib><creatorcontrib>Alam, Mostafa R.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>International ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Elbedewy, Hazem A.</au><au>Wasfy, Tamer E.</au><au>Soliman, Shaimaa S.</au><au>Sabry, Moataz M.</au><au>Awara, Amr M.</au><au>El Emam, Sharif Y.</au><au>Shafik, Heba M.</au><au>Alam, Mostafa R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prevalence and topographical characteristics of keratoconus in patients with refractive errors in the Egyptian delta</atitle><jtitle>International ophthalmology</jtitle><stitle>Int Ophthalmol</stitle><addtitle>Int Ophthalmol</addtitle><date>2019-07-01</date><risdate>2019</risdate><volume>39</volume><issue>7</issue><spage>1459</spage><epage>1465</epage><pages>1459-1465</pages><issn>0165-5701</issn><eissn>1573-2630</eissn><abstract>Purpose
To study the prevalence of keratoconus (KC) and the topographical characteristics of the affected corneas in patients with refractive errors who were seeking refractive surgery in the Egyptian delta.
Methods
A retrospective study covering four and half years (Jan 2012–June 2016) where the topographical data of 8124 participants were obtained from the records of a refractive center in the Nile delta region, Egypt. The diagnosis of KC was based on the Holladay criteria in one or both eyes, using the Pentacam scans, whereas grading of KC was based on the Amsler-Krumeich classification.
Results
The prevalence of KC was 1.12% (91/8124 participants) with 95% confidence interval 0.91–1.3. Of all the affected cases, 5 cases (5.5%) had unilateral, and the other 86 cases (94.5%) had bilateral KC. The affected and unaffected subjects did not show any significant difference regarding gender. Sixty-eight (38.4%) eyes had stage 1 KC, 53 eyes (29.9%) had stage 2, 27 eyes (15.3%) had stage 3, and 29 eyes (16.4%) had stage 4 KC. It was most prevalent (1.2%) among cases with astigmatism (
P
< 0.001).
Conclusion
Keratoconus was found in 1.12% of patients seeking refractive surgery, with no gender preference. Most cases had bilateral affection. Astigmatism was the most common refractive error to be associated with keratoconus.</abstract><cop>Dordrecht</cop><pub>Springer Netherlands</pub><pmid>29938312</pmid><doi>10.1007/s10792-018-0965-4</doi><tpages>7</tpages></addata></record> |
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| subjects | Adult Astigmatism Confidence intervals Cornea - pathology Corneal Topography - methods Egypt - epidemiology Evaluation Eye Female Follow-Up Studies Humans Keratoconus Keratoconus - complications Keratoconus - diagnosis Keratoconus - epidemiology Male Medicine Medicine & Public Health Ophthalmology Original Paper Patients Population Surveillance Prevalence Refraction, Ocular Refractive Errors - complications Refractive Errors - diagnosis Refractive Errors - epidemiology Retrospective Studies Surgery |
| title | Prevalence and topographical characteristics of keratoconus in patients with refractive errors in the Egyptian delta |
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