Add-on therapy with traditional Chinese medicine: An efficacious approach for lipid metabolism disorders
[Display omitted] Add-on therapy with traditional Chinese medicine (TCM) has been extensively researched in the intractable diseases, such as asthma, cancer, and Alzheimer’s disease. As an entirely new concept, add-on therapy of TCM has been also used to prevent and treat hyperlipidemia via lowering...
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| Veröffentlicht in: | Pharmacological research 2018-08, Vol.134, p.200-211 |
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| container_title | Pharmacological research |
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| creator | Zhang, Ying Kishi, Hiroko Kobayashi, Sei |
| description | [Display omitted]
Add-on therapy with traditional Chinese medicine (TCM) has been extensively researched in the intractable diseases, such as asthma, cancer, and Alzheimer’s disease. As an entirely new concept, add-on therapy of TCM has been also used to prevent and treat hyperlipidemia via lowering cholesterol level. However, the efficacy of add-on therapy with TCM for mediating lipid metabolism disorders remains controversial. In this review, we summarize and provide strong evidence that add-on therapy of TCM as a novel approach is efficacious and safe for hyperlipidemia associated diseases based on the mediation of lipid metabolism disorders. |
| doi_str_mv | 10.1016/j.phrs.2018.06.004 |
| format | Article |
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Add-on therapy with traditional Chinese medicine (TCM) has been extensively researched in the intractable diseases, such as asthma, cancer, and Alzheimer’s disease. As an entirely new concept, add-on therapy of TCM has been also used to prevent and treat hyperlipidemia via lowering cholesterol level. However, the efficacy of add-on therapy with TCM for mediating lipid metabolism disorders remains controversial. In this review, we summarize and provide strong evidence that add-on therapy of TCM as a novel approach is efficacious and safe for hyperlipidemia associated diseases based on the mediation of lipid metabolism disorders.</description><identifier>ISSN: 1043-6618</identifier><identifier>EISSN: 1096-1186</identifier><identifier>DOI: 10.1016/j.phrs.2018.06.004</identifier><identifier>PMID: 29935947</identifier><language>eng</language><publisher>Netherlands: Elsevier Ltd</publisher><subject>Berberine ; Biomarkers - blood ; Combination therapy ; Curcumin ; Drug Therapy, Combination ; Drugs, Chinese Herbal - therapeutic use ; Dyslipidemias - blood ; Dyslipidemias - diagnosis ; Dyslipidemias - drug therapy ; Humans ; Hyperlipidemia ; Hypolipidemic Agents - adverse effects ; Hypolipidemic Agents - therapeutic use ; Lipid Metabolism - drug effects ; Lipids - blood ; Lowering-cholesterol ; Risk Factors ; Treatment Outcome</subject><ispartof>Pharmacological research, 2018-08, Vol.134, p.200-211</ispartof><rights>2018 Elsevier Ltd</rights><rights>Copyright © 2018 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c356t-337aa0ae741b383b108e6e44448147c8c5f0f72fc2cfc6dcc6b34366b48f9d403</citedby><cites>FETCH-LOGICAL-c356t-337aa0ae741b383b108e6e44448147c8c5f0f72fc2cfc6dcc6b34366b48f9d403</cites><orcidid>0000-0003-2896-7355</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S1043661818305607$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29935947$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zhang, Ying</creatorcontrib><creatorcontrib>Kishi, Hiroko</creatorcontrib><creatorcontrib>Kobayashi, Sei</creatorcontrib><title>Add-on therapy with traditional Chinese medicine: An efficacious approach for lipid metabolism disorders</title><title>Pharmacological research</title><addtitle>Pharmacol Res</addtitle><description>[Display omitted]
Add-on therapy with traditional Chinese medicine (TCM) has been extensively researched in the intractable diseases, such as asthma, cancer, and Alzheimer’s disease. As an entirely new concept, add-on therapy of TCM has been also used to prevent and treat hyperlipidemia via lowering cholesterol level. However, the efficacy of add-on therapy with TCM for mediating lipid metabolism disorders remains controversial. In this review, we summarize and provide strong evidence that add-on therapy of TCM as a novel approach is efficacious and safe for hyperlipidemia associated diseases based on the mediation of lipid metabolism disorders.</description><subject>Berberine</subject><subject>Biomarkers - blood</subject><subject>Combination therapy</subject><subject>Curcumin</subject><subject>Drug Therapy, Combination</subject><subject>Drugs, Chinese Herbal - therapeutic use</subject><subject>Dyslipidemias - blood</subject><subject>Dyslipidemias - diagnosis</subject><subject>Dyslipidemias - drug therapy</subject><subject>Humans</subject><subject>Hyperlipidemia</subject><subject>Hypolipidemic Agents - adverse effects</subject><subject>Hypolipidemic Agents - therapeutic use</subject><subject>Lipid Metabolism - drug effects</subject><subject>Lipids - blood</subject><subject>Lowering-cholesterol</subject><subject>Risk Factors</subject><subject>Treatment Outcome</subject><issn>1043-6618</issn><issn>1096-1186</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMFu1DAQhi0EoqXlBTggH7kkjGPHSRCX1YoCUiUu9Gw547HiVTYOdhbUt8erLT0yl5nDN79mPsbeCagFCP3xUK9TynUDoq9B1wDqBbsWMOhKiF6_PM9KVlqL_oq9yfkAAIMS8JpdNcMg20F112zaOVfFhW8TJbs-8j9hm_iWrAtbiIud-X4KC2XiR3IBy_iJ7xZO3ge0GOIpc7uuKVqcuI-Jz2ENrrCbHeMc8pG7kGNylPIte-XtnOntU79hD3dffu6_Vfc_vn7f7-4rlK3eKik7a8FSp8QoezkK6EmTKtUL1WGPrQffNR4b9Kgdoh6lklqPqveDUyBv2IdLbrnq14nyZo4hI82zXaicaxpoBygWWlXQ5oJiijkn8mZN4WjToxFgzobNwZwNm7NhA9oUw2Xp_VP-aSxOnlf-KS3A5wtA5cvfgZLJGGjB4i8RbsbF8L_8v7wejgI</recordid><startdate>201808</startdate><enddate>201808</enddate><creator>Zhang, Ying</creator><creator>Kishi, Hiroko</creator><creator>Kobayashi, Sei</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-2896-7355</orcidid></search><sort><creationdate>201808</creationdate><title>Add-on therapy with traditional Chinese medicine: An efficacious approach for lipid metabolism disorders</title><author>Zhang, Ying ; Kishi, Hiroko ; Kobayashi, Sei</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c356t-337aa0ae741b383b108e6e44448147c8c5f0f72fc2cfc6dcc6b34366b48f9d403</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Berberine</topic><topic>Biomarkers - blood</topic><topic>Combination therapy</topic><topic>Curcumin</topic><topic>Drug Therapy, Combination</topic><topic>Drugs, Chinese Herbal - therapeutic use</topic><topic>Dyslipidemias - blood</topic><topic>Dyslipidemias - diagnosis</topic><topic>Dyslipidemias - drug therapy</topic><topic>Humans</topic><topic>Hyperlipidemia</topic><topic>Hypolipidemic Agents - adverse effects</topic><topic>Hypolipidemic Agents - therapeutic use</topic><topic>Lipid Metabolism - drug effects</topic><topic>Lipids - blood</topic><topic>Lowering-cholesterol</topic><topic>Risk Factors</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zhang, Ying</creatorcontrib><creatorcontrib>Kishi, Hiroko</creatorcontrib><creatorcontrib>Kobayashi, Sei</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Pharmacological research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhang, Ying</au><au>Kishi, Hiroko</au><au>Kobayashi, Sei</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Add-on therapy with traditional Chinese medicine: An efficacious approach for lipid metabolism disorders</atitle><jtitle>Pharmacological research</jtitle><addtitle>Pharmacol Res</addtitle><date>2018-08</date><risdate>2018</risdate><volume>134</volume><spage>200</spage><epage>211</epage><pages>200-211</pages><issn>1043-6618</issn><eissn>1096-1186</eissn><abstract>[Display omitted]
Add-on therapy with traditional Chinese medicine (TCM) has been extensively researched in the intractable diseases, such as asthma, cancer, and Alzheimer’s disease. As an entirely new concept, add-on therapy of TCM has been also used to prevent and treat hyperlipidemia via lowering cholesterol level. However, the efficacy of add-on therapy with TCM for mediating lipid metabolism disorders remains controversial. In this review, we summarize and provide strong evidence that add-on therapy of TCM as a novel approach is efficacious and safe for hyperlipidemia associated diseases based on the mediation of lipid metabolism disorders.</abstract><cop>Netherlands</cop><pub>Elsevier Ltd</pub><pmid>29935947</pmid><doi>10.1016/j.phrs.2018.06.004</doi><tpages>12</tpages><orcidid>https://orcid.org/0000-0003-2896-7355</orcidid></addata></record> |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Berberine Biomarkers - blood Combination therapy Curcumin Drug Therapy, Combination Drugs, Chinese Herbal - therapeutic use Dyslipidemias - blood Dyslipidemias - diagnosis Dyslipidemias - drug therapy Humans Hyperlipidemia Hypolipidemic Agents - adverse effects Hypolipidemic Agents - therapeutic use Lipid Metabolism - drug effects Lipids - blood Lowering-cholesterol Risk Factors Treatment Outcome |
| title | Add-on therapy with traditional Chinese medicine: An efficacious approach for lipid metabolism disorders |
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