The Vascularised Chamber as an In Vivo Bioreactor

Vascularisation is key to developing large transplantable tissue constructs capable of providing therapeutic benefits. The vascularised tissue engineering chamber originates from surgical concepts in tissue prefabrication and microsurgery. It serves as an in vivo bioreactor in the form of a closed,...

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Veröffentlicht in:	Trends in biotechnology (Regular ed.) 2018-10, Vol.36 (10), p.1011-1024
Hauptverfasser:	Yap, Kiryu K., Yeoh, George C., Morrison, Wayne A., Mitchell, Geraldine M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Animals Bioengineering Bioengineering - methods Biomedical engineering Biomedical materials Bioreactors Blood vessels cell therapy Drug testing Engraftment Genetic engineering Immune system Microsurgery Microsurgery - methods Neovascularization, Physiologic Prefabrication Regenerative medicine Regenerative Medicine - methods stem cells Surgery Tissue engineering transplantation vascularised chamber
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