MicroRNA-206 suppresses TGF-β signalling to limit tumor growth and metastasis in lung adenocarcinoma

MicroRNA-206 (miR-206) has demonstrated tumor suppressive effects in a variety of cancers. Numerous studies have identified aberrantly expressed targets of miR-206 that contribute to tumor progression and metastasis, however, the broader gene-networks and pathways regulated by miR-206 remain poorly...

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Veröffentlicht in:	Cellular signalling 2018-10, Vol.50, p.25-36
Hauptverfasser:	Watt, Kathleen, Newsted, Daniel, Voorand, Elena, Gooding, Robert J., Majewski, Adrianna, Truesdell, Peter, Yao, Binchen, Tuschl, Thomas, Renwick, Neil, Craig, Andrew W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Lung cancer Metastasis microRNA miR-206 Smad3 TGF-β
Online-Zugang:	Volltext
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