Platelet Releasate Proteome Profiling Reveals a Core Set of Proteins with Low Variance between Healthy Adults

Upon activation, platelets release a powerful cocktail of soluble and vesicular signals, collectively termed the "platelet releasate" (PR). Although several studies have used qualitative/quantitative proteomic approaches to characterize PR; with debated content and significant inter‐indivi...

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Veröffentlicht in:	Proteomics (Weinheim) 2018-08, Vol.18 (15), p.e1800219-n/a
Hauptverfasser:	Parsons, Martin E. M., Szklanna, Paulina B., Guerrero, Jose A., Wynne, Kieran, Dervin, Feidhlim, O'Connell, Karen, Allen, Seamus, Egan, Karl, Bennett, Cavan, McGuigan, Christopher, Gheveart, Cedric, Ní Áinle, Fionnuala, Maguire, Patricia B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adults Bioinformatics Diagnostic systems Exosomes extracellular vesicles Fingerprinting label‐free quantification platelet releasate Platelets Protein composition Proteins Proteomics Secretion tandem MS Thrombin Variability Vesicles
Online-Zugang:	Volltext
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