Intake of Protein Hydrolysates and Phenolic Fractions Isolated from Flaxseed Ameliorates TNBS‐Induced Colitis

Scope In the attempt to develop new therapeutic treatments for colitis, fractions containing phenolic compound isolate (Phi) and phenolic reduced‐flaxseed protein hydrolysate (phr‐FPH) from flaxseed are evaluated for their effects on the in vitro production of pro‐inflammatory mediators and on the c...

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Veröffentlicht in:	Molecular nutrition & food research 2018-09, Vol.62 (17), p.e1800088-n/a
Hauptverfasser:	e Silva, Fernanda G. D., Paiatto, Lisiery N., Yamada, Aureo T., Netto, Flavia M., Simioni, Patrícia U., Tamashiro, Wirla M. S. C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents, Non-Steroidal - chemistry Anti-Inflammatory Agents, Non-Steroidal - pharmacology Biotechnology Cell culture Cell proliferation Cell Survival - drug effects Colitis Colitis - chemically induced Colitis - drug therapy Colitis - etiology Colon Cytokines Cytokines - metabolism Disease Models, Animal Female Flax - chemistry flaxseed Helper cells Hydrolysates Incubation Inflammation Mediators - metabolism Inflammatory bowel disease Inflammatory diseases Interferon Lipopolysaccharides Lymphocytes Lymphocytes T Macrophages Mice Mice, Inbred BALB C Nitric oxide Nitric Oxide - metabolism peptides Phenolic compounds Phenols Phenols - pharmacology Protein Hydrolysates - pharmacology Proteins RAW 264.7 Cells Rodents Seeds Spleen Th17 Cells - drug effects Trinitrobenzenesulfonic Acid - toxicity Tumor necrosis factor-α Weight loss
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