Platinum(II) complexes of imidazophenanthroline-based polypyridine ligands as potential anticancer agents: synthesis, characterization, in vitro cytotoxicity studies and a comparative ab initio, and DFT studies with cisplatin, carboplatin, and oxaliplatin

The synthesis of the platinum(II) complexes, [Pt(AIP)(bpy)](PF 6 ) 2 ( 1 ) and [Pt(PIP)(phen)](PF 6 ) 2 ( 2 ), of anthracene- and pyrene-conjugated imidazophenanthroline ligands and their in vitro cytotoxicity toward the fibroblast cells and the HeLa cell lines are reported. MTT assay demonstrates t...

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Veröffentlicht in:Journal of biological inorganic chemistry 2018-07, Vol.23 (5), p.833-848
Hauptverfasser: Alexander, Carlson, Nithyakumar, A., Paul, M. Wilson Bosco, Arockia Samy, N.
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Sprache:eng
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