Effects of non-MHC background genes on the induction of CD4+ T cells that prevent rejection of a highly immunogenic tumor, FBL-3

This study showed that non-MHC genes common to (DBA/2 H-2d) and (DBA/1 H-2q) gave rise to suppressor T (Ta) cells in the hybrid F1 mice between C57BL/6 (B6) strain in the antl-FBL-3 tumor responses. FBL-3, a Friend virus-induced tumor cell line of B6 mouse origin, is highly immunogenic as shown by f...

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Veröffentlicht in:	International immunology 1994-06, Vol.6 (6), p.839-846
Hauptverfasser:	Morioka, Atsuo, Iwashiro, Michihiro, Matsubayashi, Yuji, Teramura, Yasuhumi, Kuribayashi, Kagemasa
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal Biological and medical sciences CD4-Positive T-Lymphocytes - immunology CD8 Antigens - immunology Cyclophosphamide - pharmacology Cytotoxicity, Immunologic - genetics Female Fundamental and applied biological sciences. Psychology Fundamental immunology Hybridization, Genetic - genetics Hybridization, Genetic - immunology Immunobiology Lymphocyte Culture Test, Mixed Male Mice Mice, Inbred Strains Modulation of the immune response (stimulation, suppression) Neoplasm Transplantation Neoplasms, Experimental - immunology Neoplasms, Experimental - pathology non-MHC genes suppressor T cell T-Lymphocyte Subsets - immunology Tumor Cells, Cultured tumor immunity
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