Comparison of targeted next generation sequencing (NGS) versus isolated BRAF V600E analysis in patients with metastatic melanoma

Molecular testing on advanced metastatic melanoma is critical for guiding targeted therapy. Traditionally, this analysis has relied on isolated BRAF V600E analysis; however, more recently targeted next generation sequencing (NGS) is being utilized. The clinical utility of BRAF V600E allele-specific...

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Veröffentlicht in:	Virchows Archiv : an international journal of pathology 2018-09, Vol.473 (3), p.371-377
Hauptverfasser:	Zhu, Meng-Lei, Zhou, Lan, Sadri, Navid
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Brief Report Medicine Medicine & Public Health Melanoma Metastases Metastasis Molecular chains Mutation Pathology Patients
Online-Zugang:	Volltext
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