Photodynamic inactivation of Aeromonas hydrophila by cationic phthalocyanines with different hydrophobicity

Antibacterial photodynamic therapy is a pioneering method for the inactivation of pathogenic bacteria. Four tetra alkyl-substituted cationic phthalocyanines with different hydrocarbon chains attached to the pyridyloxy group were synthesized. These photodynamic sensitizers were studied for antibacter...

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Veröffentlicht in:	FEMS microbiology letters 2009-05, Vol.294 (2), p.133-140
Hauptverfasser:	Kussovski, Veselin, Mantareva, Vanya, Angelov, Ivan, Orozova, Petya, Wöhrle, Dieter, Schnurpfeil, Günter, Borisova, Ekaterina, Avramov, Latchezar
Format:	Artikel
Sprache:	eng
Schlagworte:	Aeromonas hydrophila Aeromonas hydrophila - drug effects Aeromonas hydrophila - radiation effects Antiinfectives and antibacterials Bacteria Bacteriology Biological and medical sciences Cations Cell density Deactivation Dose-Response Relationship, Drug Dose-Response Relationship, Radiation Drug Resistance, Multiple, Bacterial Etiology Fundamental and applied biological sciences. Psychology Gram-Negative Bacterial Infections - drug therapy Humans Hydrocarbons Hydrophobic and Hydrophilic Interactions Hydrophobicity Inactivation Indoles - administration & dosage Indoles - pharmacokinetics Irradiation Light - adverse effects light dose Microbiology Miscellaneous Molecular chains Multidrug resistance Photochemotherapy photodynamic inactivation Photodynamic therapy Photosensitizing Agents - administration & dosage Photosensitizing Agents - pharmacokinetics phthalocyanine Zn(II) complexes Radiation
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