Inflammation of brown/beige adipose tissues in obesity and metabolic disease

Many of the comorbidities of obesity, including type 2 diabetes and cardiovascular diseases, are related to the low‐grade chronic inflammation of white adipose tissue. Under white adipocyte stress, local infiltration of immune cells and enhanced production of pro‐inflammatory cytokines together redu...

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Veröffentlicht in:	Journal of internal medicine 2018-11, Vol.284 (5), p.492-504
Hauptverfasser:	Villarroya, F., Cereijo, R., Gavaldà‐Navarro, A., Villarroya, J., Giralt, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Adipogenesis Adipose tissue Adipose tissue (brown) Body fat brown adipose Browning Cardiovascular diseases cytokine Cytokines Diabetes mellitus Diabetes mellitus (non-insulin dependent) Energy expenditure Energy storage Heart diseases Hyperglycemia Hyperlipidemia Immune system Infiltration Inflammation Insulin macrophage Metabolic disorders Metabolic syndrome Metabolism Metabolites Obesity Substrates Thermogenesis
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